Type IITRK inhibitor3 (Compound 18d) is a Type IITRK inhibitor with IC50 values of 0.82 nM, 1.82 nM, and 0.12 nM against TRKAWT, TRKAG595R, and TRKAG667C, respectively. It exhibits antitumor activity.
Target:
Trk receptor
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