PLpro-IN-9 (Compound 14e) is an inhibitor of SARS-CoV-2 PLpro, with an IC50 of 12.0 µM and a KD of 1.86 µM. It exhibits low cytotoxicity but has poor metabolic stability. PLpro-IN-9 is suitable for research on the coronavirus.
Target:
SARS-CoV
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