IHMT-15130 is a potent and irreversible BMX kinase inhibitor (IC50=1.47 nM). It suppresses the secretion of inflammatory cytokines, obstructs inflammatory signaling pathways, and alleviates angiotensin II-induced myocardial hypertrophy in mice. IHMT-15130 shows potential for research in myocardial hypertrophy.
Target:
BTK
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