Clonixeril (NSC 335504) is a non-nucleotide modulator of hSTING. It exhibits weak agonistic activity at micromolar concentrations and can antagonize the hSTINGWT pathway at low femtomolar (10 -15 M) and even attomolar (10 -18 M) concentrations in some cases. Clonixeril inhibits hSTING oligomerization at concentrations ranging from 1 aM to 1 pM.
Molecular Weight:
336.77
CAS Number:
[21829-22-1]
Formula:
C16H17ClN2O4
Target:
STING
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