DJ-89 (Compound 77) is a potent soluble epoxide hydrolase (sEH) inhibitor with an IC50 value of 0.51 nM. It effectively inhibits the hydrolysis of epoxyeicosatrienoic acids (EETs), thereby reducing the production of inflammatory substances. DJ-89 holds potential for research into both acute and chronic inflammatory diseases, such as rheumatoid arthritis.
Target:
Epoxide Hydrolase
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