JNK2/3-IN-1 (Compound 56d) is an irreversible covalent inhibitor of c-Jun N-terminal kinases 2/3 (JNK2/3), with IC50 values of 830 nM and 1909 nM, respectively. JNK2/3-IN-1 is potentially useful for research in neurodegenerative diseases such as Parkinsons and Alzheimers, as well as fibrotic diseases.
Target:
JNK
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