CLM296 is a potent and selective inhibitor of ALDH1A3, with an IC50 of 2 nM. It does not exhibit off-target effects on the highly homologous ALDH1A1 isoform. CLM296 is capable of inhibiting ALDH1A3-driven breast cancer metastasis and can be utilized in the study of triple-negative breast cancer (TNBC).
Molecular Weight:
430.5
CAS Number:
[3067837-25-3]
Formula:
C29H22N2O2
Target:
Dehydrogenase
T211059
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