MAO-B-IN-45, CAS [[3069915-36-9]] Preis auf Anfrage

Product Overview

• Article Name: MAO-B-IN-45, CAS [[3069915-36-9]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T211128
• Supplier Catalog Number: T211128
• Alternative Catalog Number: TGM-T211128-10MG,TGM-T211128-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

MAO-B-IN-45 is a dual inhibitor of ferroptosis and MAO-B. It selectively inhibits MAO-B with an IC50 of 87.47 nM, demonstrating a selectivity over MAO-A by more than 229 times. In vitro, MAO-B-IN-45 exhibits significant anti-ferroptosis activity by modulating iron metabolism pathways and the GSH-GPX4 axis. Additionally, it improves cognitive and behavioral deficits in 3*Tg (APP/Tau/Ps1) Alzheimers disease mice and significantly reduces levels of ferritin heavy chain 1 (FTH1), beta-amyloid protein (APP), and Tau protein phosphorylation (p-Tau) in their brains.

Product Properties

• Molecular Weight: 315.75
• CAS Number: [3069915-36-9]
• Formula: C17H14ClNO3
• Target: Glutathione Peroxidase|||ROS|||Monoamine Oxidase|||Microtubule Associated|||Beta Amyloid|||Ferroptosis

Images

T211128