Amb929 (ZINC000002782982), an nsp3 ligand, is a drug active against SARS-CoV-2. It inhibits the replication of SARS-CoV-2-mNG in VeroE6 cells with an EC50 value of 34.7 µM. Amb929 exhibits limited to moderate cytotoxicity in VeroE6 cells (CC50: 281 µM) and also suppresses the replication of SARS-CoV-2-mNG in human airway epithelium (HAE).
Molecular Weight:
513.61
CAS Number:
[438196-25-9]
Formula:
C29H27N3O4S
Target:
SARS-CoV
T211135
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