DF-006 is an innovative orally active agonist of ALPK1 (alpha-kinase 1). It stimulates the innate immune response in the liver by activating the NF-kappaB pathway. DF-006 effectively reduces serum levels of hepatitis B virus (HBV) DNA (EC50 = 2.7 pM), HBsAg, and HBeAg, demonstrating potent antiviral activity, making it suitable for immunotherapy research in chronic hepatitis B (CHB).
Molecular Weight:
805.57
CAS Number:
[2311947-41-6]
Formula:
C25H34FN5O18P2S
Target:
HBV
T211143
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