Antibacterialagent 282 (Compound CP7) is a selenium-containing derivative of Ciprofloxacin that serves as an antibacterial agent. It exhibits significant activity against both Gram-positive and Gram-negative bacteria, with MICs ranging from 0.1-1.56 µg/mL and 0.1-3.13 µg/mL, respectively (MBCs are 0.2-1.56 µg/mL and 0.39-12.5 µg/mL). Additionally, Antibacterialagent 282 effectively disrupts and prevents P. aeruginosa biofilm formation and significantly inhibits the DNA gyrase of E. coli.
Target:
Antibacterial|||Antibiotic
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