INCB126503, CAS [[2640089-88-7]] Preis auf Anfrage

Product Overview

• Article Name: INCB126503, CAS [[2640089-88-7]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T211162
• Supplier Catalog Number: T211162
• Alternative Catalog Number: TGM-T211162-10MG,TGM-T211162-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

INCB126503 is an orally active and selective inhibitor of FGFR2/3, with IC50 values of 70 nM for FGFR1, 2.1 nM for FGFR2, 1.2 nM for FGFR3, 0.92 nM for FGFR3-V555L, 0.85 nM for FGFR3-V555M, and 64 nM for FGFR4. This compound inhibits FGFR signaling in vivo without causing hyperphosphatemia and demonstrates antitumor efficacy in xenograft models with FGFR3 genetic alterations.

Product Properties

• Molecular Weight: 470.57
• CAS Number: [2640089-88-7]
• Formula: C27H30N6O2
• Target: FGFR

Images

T211162