A2073 is a flavonoid derivative that inhibits the proliferation of erythroleukemia cells by inducing cell cycle arrest and suppressing the MAPK, NF-kappaB, and PI3K signaling pathways. It forms stable interactions with cell cycle-related proteins (CDK1, CCNA2, PRIM1). In a zebrafish xenograft tumor model, A2073 demonstrates significant anti-tumor cell proliferation activity while maintaining low toxicity. A2073 is suitable for research in acute erythroleukemia.
Molecular Weight:
559.65
CAS Number:
[2834742-70-8]
Formula:
C33H37NO7
Target:
NF-kappaB|||Akt|||p38 MAPK|||PI3K
T211237
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