DC-174 is an orally active snake venom metalloproteinase (SVMP) inhibitor with broad-spectrum activity against various snake venom SVMPs. It binds directly to the active site of SVMP through a zinc-binding group, inhibiting its enzymatic activity and procoagulant toxicity. DC-174 significantly prolongs the survival time of mice under snake venom attack and is applicable for researching emergency treatment of snakebites.
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