PI4Kbeta/PKG-IN-2 (Compound 20) is an orally active dual inhibitor that targets phosphatidylinositol 4-kinase beta (PI4Kbeta) and cGMP-dependent protein kinase (PKG) in Plasmodium. It demonstrates significant inhibitory effects on Plasmodium and holds potential for use in malaria research.
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PI4K|||PKA|||Parasite
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