AR antagonist 12, CAS [[2902679-42-7]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T211304
Supplier Catalog Number:
T211304
Alternative Catalog Number:
TGM-T211304-10MG,TGM-T211304-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
AR antagonist 12 (compound 20i) is an orally active androgen receptor antagonist, demonstrating IC50 values of 119.3 µM for wt-AR and 98.2 µM for AR-F877L. It induces a dose- and time-dependent reduction in the protein levels of AR, AR-v7, and PSA. AR antagonist 12 exhibits anticancer activity, making it useful in the study of Enzalutamide-resistant prostate cancer.
Molecular Weight:
484.47
CAS Number:
[2902679-42-7]
Formula:
C24H23F3N6O2
Target:
Androgen Receptor
T211304
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