Mesutoclax (ICP-248) (Compound 5) is a selective BCL-2 inhibitor with an IC50 of 1.54 nM, demonstrating weak activity against BCL-XL (IC50: >1000 nM). It inhibits the viability of RS4,11 cells with an IC50 of 2.75 nM and can be utilized in cancer research.
Molecular Weight:
884.44
Purity:
98.96%
CAS Number:
[2760536-87-4]
Formula:
C45H50ClN7O8S
Target:
Bcl-2 Family
T211322
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