Bis-Cl-ANT-ATP (tetrasodium) is a fluorescent ATP derivative that undergoes spontaneous isomerization. It selectively inhibits the adenylate cyclase toxin CyaA of Bordetella pertussis, with greater efficacy than mammalian adenylyl cyclases AC1, AC2, and AC5, exhibiting \[K_i\] values of 16, 1,700, 2,400, and 1,600 nM, respectively. Bis-Cl-ANT-ATP (tetrasodium) can be utilized in pertussis research.
Target:
Antibacterial|||AChR
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