Osunprotafib hydrochloride, CAS [[2986745-48-4]] Preis auf Anfrage

Product Overview

• Article Name: Osunprotafib hydrochloride, CAS [[2986745-48-4]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T211442
• Supplier Catalog Number: T211442
• Alternative Catalog Number: TGM-T211442-10MG,TGM-T211442-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: ABBV-CLS-484 hydrochloride

Product Description

Osunprotafib (ABBV-CLS-484) hydrochloride is an orally active, selective inhibitor targeting the active sites of PTPN1 (IC50: 2.5 nM) and PTPN2 (IC50: 1.8 nM). It shows 6-8 times weaker activity towards PTPN9 and no detectable activity against SHP-1 or SHP-2. This compound enhances the sensitivity of human cancer cell lines to IFNgamma. By boosting JAK-STAT signaling and reducing T cell dysfunction, Osunprotafib hydrochloride exhibits potent antitumor immunity.

Product Properties

• Molecular Weight: 421.92
• CAS Number: [2986745-48-4]
• Formula: C17H25ClFN3O4S
• Target: Phosphatase

Images

T211442