DHC-286 is a molecular glue degrader that targets GSPT1. It recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, facilitating its ubiquitination and subsequent degradation via the proteasome, which induces cytotoxic effects. DHC-286 holds potential for cancer research.
Molecular Weight:
475.42
CAS Number:
[2920443-08-7]
Formula:
C23H20F3N3O5
Target:
PROTACs|||Molecular Glues
T211486
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