EGFR-IN-167, CAS [[3052761-67-5]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T211515
Supplier Catalog Number:
T211515
Alternative Catalog Number:
TGM-T211515-10MG,TGM-T211515-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
EGFR-IN-1671 is a selective EGFR inhibitor with an IC50 value of 0.19 nM. It effectively inhibits various EGFR mutants, showing IC50 values of 0.109 nM for EGFR(L858R), 0.75 nM for EGFR(C797S), and less than 0.05 nM for EGFR(del19). EGFR-IN-1671 covalently binds to the catalytically conserved lysine of EGFR in live mammalian cells. By inhibiting EGFR autophosphorylation, this compound demonstrates excellent antiproliferative activity. EGFR-IN-1671 is applicable in research on non-small cell lung cancer (NSCLC), glioblastoma, and various solid tumors.
Molecular Weight:
467.47
CAS Number:
[3052761-67-5]
Formula:
C20H22FN3O7S
Target:
EGFR
T211515
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