PI3Kdelta/HDAC6-IN-1, CAS [[3075011-99-0]] Preis auf Anfrage

Product Overview

• Article Name: PI3Kdelta/HDAC6-IN-1, CAS [[3075011-99-0]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T211563
• Supplier Catalog Number: T211563
• Alternative Catalog Number: TGM-T211563-10MG,TGM-T211563-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PI3Kdelta/HDAC6-IN-1 (Compound 22E) is an orally active dual inhibitor of PI3Kdelta and HDAC6, with IC50 values of 2.4 nM and 6.2 nM, respectively. It exhibits potent antiproliferative effects against non-Hodgkins lymphoma (NHL) cells and demonstrates antitumor activity in vivo without significant toxicity. PI3Kdelta/HDAC6-IN-1 induces cell cycle arrest at the G0/G1 phase and triggers apoptosis. Additionally, it inhibits the PI3K/AKT/mTOR signaling pathway and enhances the acetylation levels of alpha-tubulin and histone H3.

Product Properties

• Molecular Weight: 650.73
• CAS Number: [3075011-99-0]
• Formula: C34H38N10O4
• Target: ROS|||Microtubule Associated|||PI3K|||HDAC|||Caspase|||Bcl-2 Family|||Histone Methyltransferase|||Apoptosis

Images

T211563