ASIC1a antagonist-1, CAS [[1787243-08-6]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T211667
Supplier Catalog Number:
T211667
Alternative Catalog Number:
TGM-T211667-10MG,TGM-T211667-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
ASIC1a antagonist-1 (Compound 5b) is an orthosteric non-competitive antagonist of the acid-sensing ion channel 1a (ASIC1a) with an IC50 of 27 nM at pH 6.7. It alters the pH dependency of ASIC1a activation and suppresses its maximum response. Additionally, ASIC1a antagonist-1 completely inhibits the induction of long-term potentiation (LTP) in the CA3-CA1 pathway. This compound is useful for research into brain diseases and pathologies.
Molecular Weight:
499.86
CAS Number:
[1787243-08-6]
Formula:
C23H29Cl3N4O2
Target:
Sodium Channel
T211667
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