Cs-2d is a selective inhibitor of the ceramide synthase Cer1. It exhibits potent inhibitory activity against Cer1 in C. neoformans, while maintaining low off-target effects on human hCerS1. Cs-2d demonstrates strong antifungal activity and significantly suppresses fungal growth. It is applicable in studies of invasive fungal infections.
Molecular Weight:
436.38
CAS Number:
[2928129-57-9]
Formula:
C22H27Cl2N3O2
Target:
Antifungal|||Acyltransferase
T211818
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