MRT-23227 is a molecular glue degrader targeting cereblon (CRBN). It forms a ternary complex with CRBN and G3BP2, which activates the ubiquitin-proteasome system to degrade G3BP2. MRT-23227 shows potential for research in G3BP2-related cancers (such as breast cancer and lung cancer) and neurodegenerative diseases.
Molecular Weight:
409.87
CAS Number:
[3050683-03-6]
Formula:
C22H20ClN3O3
Target:
PROTACs|||Molecular Glues
T211823
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