Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces autophagy and apoptosis.
Molecular Weight:
868.44
Purity:
99.97%
CAS Number:
[1257044-40-8]
Formula:
C45H50ClN7O7S
Target:
Autophagy|||Bcl-2 Family
T2119
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