RNA MTase-IN-1 (Compound 47) is an inhibitor of RNA methyltransferase (RNA MTase), exhibiting an IC50 of 68 µM against 16S rRNA (m1A1408) methyltransferase (NpmA). It demonstrates significant inhibitory activity against aminoglycoside resistance linked to pathogens and is applicable in research on antibiotic-resistant bacterial infections.
Target:
Antibacterial|||Others
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