JAK1-IN-18, CAS [[2459377-98-9]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T212087
Supplier Catalog Number:
T212087
Alternative Catalog Number:
TGM-T212087-10MG,TGM-T212087-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
JAK1-IN-18 (Example 2) is a selective JAK1 inhibitor with an IC50 value of 0.15 nM, demonstrating significantly greater inhibitory potency for JAK1 compared to JAK2 and JAK3. It significantly reduces inflammation in ulcerative colitis (UC) mouse models induced by DSS and Crohns disease (CD) rat models induced by DNBS. JAK1-IN-18 is applicable for research into autoimmune diseases (such as inflammatory bowel disease), viral infections (such as hepatitis B virus infection), and cancers (such as hematologic malignancies).
Molecular Weight:
366.37
CAS Number:
[2459377-98-9]
Formula:
C16H20F2N6O2
Target:
JAK
T212087
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