Nurr1 Agonist 14 (Compound 32) is a Nurr1 agonist with an EC50 of 0.09 µM for Nurr1. It exhibits significant neuroprotective activity without being hindered by residual DHODH inhibition. This compound can upregulate neuroprotective genes in dopaminergic neurons, such as SOD2, SESN3, BIRC5, XIAP, FLRT2, and CRMP4. Nurr1 Agonist 14 is useful for studying neurodegenerative diseases such as Alzheimers disease (AD), Parkinsons disease (PD), and multiple sclerosis (MS).
Target:
Others|||Survivin|||Calcium Channel|||NR4A|||IAP
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