Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (beta5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (beta1) and trypsin-like (beta2) proteolytic sites (IC50: 31/3500 nM).
Molecular Weight:
361.03
Purity:
99.77%
CAS Number:
[1072833-77-2]
Formula:
C14H19BCl2N2O4
Target:
Proteasome|||Caspase|||Autophagy
T2122
* VAT and and shipping costs not included. Errors and price changes excepted
