Tuspetinib dihydrochloride, CAS [[3037216-20-6]] Preis auf Anfrage

Product Overview

• Article Name: Tuspetinib dihydrochloride, CAS [[3037216-20-6]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T212318
• Supplier Catalog Number: T212318
• Alternative Catalog Number: TGM-T212318-10MG,TGM-T212318-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: HM43239 dihydrochloride

Product Description

Tuspetinib (HM43239) dihydrochloride is a selective FLT3 inhibitor with oral bioactivity, exhibiting IC50 values of 1.1 nM for FLT3 wild type, 1.8 nM for FLT3ITD mutant type, and 1.0 nM for FLT3D835Y mutant type. As a reversible type I inhibitor, it directly suppresses FLT3 kinase activity and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib dihydrochloride inhibits the proliferation of leukemia cells and induces apoptosis (apoptosis).

Product Properties

• Molecular Weight: 573.99
• CAS Number: [3037216-20-6]
• Formula: C29H35Cl3N6
• Target: Apoptosis|||FLT

Images

T212318