HIV-1-IN-83 (Compound 18E) is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1. It demonstrates an IC50 of 0.45 µM against wild-type HIV-1 reverse transcriptase. HIV-1-IN-83 exhibits potent antiviral activity against both wild-type and mutant HIV-1 strains and enhances drug resistance in Y188L and RES056 mutants. The compound is non-toxic up to a concentration of 11.088 µM.
Target:
HIV Protease|||Reverse Transcriptase
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