CDN prodrug-1 (Compound 2) acts as a STING ligand. It is composed of a cyclic dinucleotide (CDN) linked by a diproline peptide. Once CDN prodrug-1 is internalized into lysosomes by cathepsins, it can be cleaved to release the parent CDN. Additionally, CDN prodrug-1 can be synthesized into nanoparticles for drug delivery research.
Target:
STING
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