PROTAC SGK3 degrader-2, CAS [[2381196-78-5]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC SGK3 degrader-2, CAS [[2381196-78-5]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T212560
• Supplier Catalog Number: T212560
• Alternative Catalog Number: TGM-T212560-10MG,TGM-T212560-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PROTACSGK3degrader-2 is the cis-diastereomer of PROTACSGK3degrader-1 (SGK3-PROTAC1), featuring a cis-hydroxy group in its VH032 section, which prevents binding to the VHL E3 ligase. This compound inhibits SGK3, SGK1, and S6K1 with IC50 values of 0.6 µM, 1.4 µM, and 1.7 µM, respectively, but does not degrade SGK3. It serves as a control compound for studying the specific degradation effects mediated by SGK3-PROTAC1.

Product Properties

• Molecular Weight: 1157.38
• CAS Number: [2381196-78-5]
• Formula: C57H73FN10O11S2
• Target: PROTACs|||SGK

Images

T212560