ARUK2010489 (Compound 23) is a potent, selective, and brain-penetrant NUAK1 inhibitor with a pIC50 of 8.7, also exhibiting partial inhibitory activity against CDK2, CDK4, and CDK6 at micromolar concentrations, and it is applied in neurological disease research, including mechanistic studies related to Alzheimers disease.
Molecular Weight:
406.53
Purity:
99.85%
Formula:
C23H30N6O
Target:
CDK|||AMPK
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