GPS167 is a specific small-molecule splicing regulator and SRSF10 inhibitor that modulates BCLAF1 alternative splicing with an IC50 of 2 µM in human colorectal HCT116 cells, while also directly inhibiting CLK1, CLK2, and CLK4 but not SRPK1 or DYRK1A, positioning it as a mechanistically well-defined probe for studying spliceosome regulation and kinase-dependent RNA processing.
Molecular Weight:
335.38
Purity:
99.13%
CAS Number:
[3034312-19-8]
Formula:
C17H13N5OS
Target:
Others
T212632
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