GTPL547 is a potent quorum sensing system antagonist specifically targeting the PqsR (MvfR) transcriptional regulator in Pseudomonas aeruginosa (IC50 = 12 nM). By halting the PQS-mediated gene transcription cascade, it completely suppresses the secretion of lethal virulence factors like pyocyanin and the irreversible assembly of biofilms, providing a critical lead compound for tackling multidrug-resistant infections.
Molecular Weight:
325.45
Purity:
99.37%
CAS Number:
[174689-38-4]
Formula:
C21H27NO2
Target:
Antibacterial
T212734
* VAT and and shipping costs not included. Errors and price changes excepted
