MLS-0322825 is a highly selective, orally active, low-molecular-weight protein tyrosine phosphatase (LMPTP/LMW-PTP) non-competitive inhibitor that exhibits potent inhibitory activity against the LMPTP-A subtype (IC50 = 3.3 µM) and weaker inhibitory activity against the LMPTP-B subtype (IC50 ~ 40 µM). MLS-0322825 effectively increases IR phosphorylation levels in the liver and reduces blood glucose and insulin levels in obese mice. MLS-0322825 exhibits potential antitumor activity and can be used in tumor research.
Molecular Weight:
331.46
Purity:
99.98%
CAS Number:
[853310-63-1]
Formula:
C22H25N3
Target:
Phosphatase
T212833
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