EGFR/COX-2-IN-3 is a highly selective dual-target inhibitor of EGFR and COX-2, with IC50 values of 0.098 µM and 0.05 µM for the two targets respectively. Pharmacological prediction Results: show that it possesses good oral bioavailability and blood-brain barrier penetration ability. Meanwhile, it exhibits significant analgesic effects and anti-glioblastoma pharmacological activity, and can be applied to mechanism and efficacy research of glioblastoma and other tumors.
Molecular Weight:
375.47
Purity:
99.96%
CAS Number:
[3121638-16-9]
Formula:
C22H25N5O
Target:
EGFR
T212904
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