NCGC00685960, CAS [[3091000-99-3]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T213014
Supplier Catalog Number:
T213014
Alternative Catalog Number:
TGM-T213014-10MG,TGM-T213014-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
NCGC00685960 is a potent inhibitor of nicotinamide N-methyltransferase (NNMT) with an IC50 of less than 10 nM. This compound exhibits strong anti-tumor activity, enhances H3K27 trimethylation in ovarian cancer cells, and suppresses alpha-SMA expression in NNMT-expressing ovarian fibroblasts. It also reduces 1-MNA levels in cancer-associated fibroblasts (CAFs), reverses low SAM and H3K27 methylation, and significantly diminishes collagen contractility. NCGC00685960 is valuable for cancer research.
Molecular Weight:
458
CAS Number:
[3091000-99-3]
Formula:
C24H32ClN5O2
Target:
Others
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