SARS-CoV-2 nsp14-IN-6 (Compound 35) ammonium is an inhibitor of the SARS-CoV-2 Nsp14 MTase, exhibiting an IC50 of 0.24 µM. This compound demonstrates significant antiviral activity by inhibiting the replication of SARS-CoV-2. Additionally, SARS-CoV-2 nsp14-IN-6 ammonium has enhanced lipophilicity, which improves cellular permeability, making it a valuable tool for human coronavirus research.
Target:
SARS-CoV
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