BTT-3034, a sulfonamide derivative, functions as an alpha2beta1 integrin inhibitor. It effectively inhibits cell adhesion to rat tail collagen I, with an EC50 value of 160 nM and an Emax value of 86%. Additionally, BTT-3034 impedes collagen binding through the alpha2 variant carrying the conformation-activating E318W mutation.
Molecular Weight:
467.56
CAS Number:
[1259029-47-4]
Formula:
C22H21N5O3S2
Target:
Integrin
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