Afatinib, CAS [[850140-72-6]]

Product Overview

• Article Name: Afatinib, CAS [[850140-72-6]]
• Biozol Catalog Number: TGM-T21312
• Supplier Catalog Number: T21312
• Alternative Catalog Number: TGM-T21312-1MLX10MM(INDMSO),TGM-T21312-5MG,TGM-T21312-10MG,TGM-T21312-25MG,TGM-T21312-50MG,TGM-T21312-100MG,TGM-T21312-200MG,TGM-T21312-500MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Afatinib free base , BIBW 2992

Product Description

Afatinib (BIBW 2992) is an irreversible inhibitor of the EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M, and HER2) with IC50s of 0.5 nM, 0.4 nM, 10 nM, and 14 nM, respectively.

Product Properties

• Molecular Weight: 485.94
• Purity: 97.56%
• CAS Number: [850140-72-6]
• Formula: C24H25ClFN5O3
• Target: Autophagy|||EGFR|||Apoptosis|||Akt|||p38 MAPK|||c-Met/HGFR

Images

T21312