Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.
Molecular Weight:
288.3
CAS Number:
[114560-48-4]
Formula:
C15H16N2O4
Target:
Others
T21316
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