MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase and apoptosis in tumor cells that overexpress KSP.
Molecular Weight:
459.5
CAS Number:
[845256-65-7]
Formula:
C25H28F3N3O2
Target:
Others|||Apoptosis|||Lipoxygenase|||Kinesin
T21321
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