TAK-441 is an orally active inhibitor of Hedgehog signaling(IC50 = 4.4 nM) with potent antitumor activity. TAK-441 suppresses transcription factor Gli1 mRNA expression and tumor growth.
Molecular Weight:
576.56
Purity:
98.79%
CAS Number:
[1186231-83-3]
Formula:
C28H31F3N4O6
Target:
Hedgehog/Smoothened
T21325
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