Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3alpha (IC50: 500nM), GSK-3beta (IC50: 650nM), JNK (IC50~3-10µM).
Molecular Weight:
267.33
CAS Number:
[496864-16-5]
Formula:
C16H17N3O
Target:
Others|||CDK|||CFTR|||ERK|||JNK|||GSK-3
T21377
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