SB-505124 hydrochloride, CAS [[356559-13-2]]

Product Overview

• Article Name: SB-505124 hydrochloride, CAS [[356559-13-2]]
• Biozol Catalog Number: TGM-T21637
• Supplier Catalog Number: T21637
• Alternative Catalog Number: TGM-T21637-1MG,TGM-T21637-5MG,TGM-T21637-10MG,TGM-T21637-25MG,TGM-T21637-50MG,TGM-T21637-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: SB505124 hydrochloride , SB 505124 hydrochloride

Product Description

SB-505124 hydrochloride (SB505124 hydrochloride) is an orally available, selective and potent inhibitor of TGF-beta type I receptors (ALK4, ALK5, ALK7) with IC50 values of 129 nM and 47 nM for ALK4 and ALK5, respectively. SB-505124 hydrochloride inhibits IL-6 production by synovial explants and reduces Th17 differentiation in mice by decreasing Il17a and Rorc gene expression and IL-17 protein production.SB-505124 hydrochloride is used in the study of colorectal cancer.

Product Properties

• Molecular Weight: 371.86
• Purity: 0.9871
• CAS Number: [356559-13-2]
• Formula: C20H22ClN3O2
• Target: ALK|||TGF-beta/Smad

Images

T21637