Vandetanib hydrochloride (D6474 hydrochloride) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity with an IC50 of 40 nM. It also exhibits activity against VEGFR3/FLT4 tyrosine kinase activity (IC50 = 110 nM) and EGFR/HER1 (IC50 = 500 nM) [1].
Molecular Weight:
511.81
CAS Number:
[524722-52-9]
Formula:
C22H25BrClFN4O2
Target:
Apoptosis|||VEGFR|||Autophagy|||Others
T21641
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