IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1gamma3 and CK1epsilon, but does not inhibit CK1alpha [1] [2].
Molecular Weight:
484.59
Purity:
0.9838
CAS Number:
[687561-60-0]
Formula:
C22H17FN4O2S3
Target:
Wnt/beta-catenin
T21650
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